
By Amy Norton Last Updated: 2005-10-26 10:21:44 -0400 (Reuters Health)
NEW YORK (Reuters Health) - Although both marijuana and tobacco smoke are packed with cancer-causing chemicals, other qualities of marijuana seem to keep it from promoting lung cancer, according to a new report.
The difference rests in the often opposing actions of the nicotine in tobacco and the active ingredient, THC, in marijuana, says Dr. Robert Melamede of the University of Colorado in Colorado Springs.
He reviewed the scientific evidence supporting this contention in a recent issue of Harm Reduction Journal.
Whereas nicotine has several effects that promote lung and other types of cancer, THC acts in ways that counter the cancer-causing chemicals in marijuana smoke, Melamede explained in an interview with Reuters Health.
"THC turns down the carcinogenic potential," he said.
For example, lab research indicates that nicotine activates a body enzyme that converts certain chemicals in both tobacco and marijuana smoke into cancer-promoting form. In contrast, studies in mice suggest that THC blocks this enzyme activity.
Another key difference, Melamede said, is in the immune system effects of tobacco and marijuana. Smoke sends irritants into the respiratory system that trigger an immune-regulated inflammatory response, which involves the generation of potentially cell-damaging substances called free radicals. These particles are believed to contribute to a range of diseases, including cancer.
But cannabinoids -- both those found in marijuana and the versions found naturally in the body -- have been shown to dial down this inflammatory response, Melamede explained.
Another difference between tobacco and marijuana smoking, he said, has to do with cells that line the respiratory tract. While these cells have receptors that act as docks for nicotine, similar receptors for THC and other cannabinoids have not been found.
Nicotine, Melamede said, appears to keep these cells from committing "suicide" when they are genetically damaged, by smoking, for instance. When such cells do not kill themselves off, they are free to progress into tumors.
THC, however, does not appear to act this way in the respiratory tract -- though, in the brain, where there are cannabinoid receptors, it may have the beneficial effect of protecting cells from death when they are damaged from an injury or stroke, according to Melamede.
All of this, he said, fits in with population studies that have failed to link marijuana smoking with a higher risk of lung cancer -- though there is evidence that pot users have more respiratory problems, such as chronic cough and frequent respiratory infections.
If marijuana does not promote lung cancer, that could factor into the ongoing debate over so-called medical marijuana. Melamede said he believes "marijuana has loads of medicinal value," for everything from multiple sclerosis, to the chronic pain of arthritis, to nausea caused by cancer treatment.
U.S. government officials, however, maintain that the evidence for medical marijuana is not there. Ten states allow people to use marijuana with a doctor's prescription, but the Supreme Court has ruled that federal law trumps state law.
artwork - magic molecule by alex grey - see http://www.alexgrey.com !!
source - http://www.pamf.org/health/healthinfo/reutershome_top.cfm?fx=article&id=25449
Legalize it and advertize it
Legalize it and advertize it
There is one basic tenet that has remained permanent truth, regardless of
the claim-of-the-day spouted by modern science, and that is that nicotine
is a health BENEFIT for smokers!
The medicalization of everyday life, making medical issues of behaviors is
disease mongering, trying to convince well people that they're sick,
slightly sick people that they're very ill, or that they are at risk from
smokers is big business. Disease mongering creates the disease and then
offers the cure. Disease mongering is the sells false science that is paid
for in order to grow markets for those who sell and deliver treatments.
Like second hand smoke. Special interest has jumped into the fray too many
times with the “answer”, their drugs, to “save” us from ourselves.
The CATO Institute (The Second-Hand Smoke Charade
http://www.cato.org/pub_display.php...) and Sloan Kettering
(http://www.mskcc.org/mskcc/html/12463.cfm) contradict their findings,
alot! Smoking rates have decreased considerably, yet asthma rates have
skyrocketed 500%! The global warming "crisis" looked like a sure thing too
until it was blown out of the water by those who knew this was a scam.
Anyone looking at all can see this second hand smoke nonsense has also been
completely debunked. Have to give it to pharma though, it IS a brilliant
marketing scam using our own uneducated government officials against us.
We need to control the out-of-control tobacco control brigade like the
tobacco plant can do with it's predators!
Tobacco Plants Control Pollinators by Dosing Their Nectar With Nicotine: h
ttp://blogs.discovermagazine.com/80beats/2008/08/29/tobacco-plants-control-
pollinators-by-dosing-their-nectar-with-nicotine/
When Caterpillars Attack,
Tobacco Plants Use Their Own Spit Against Them: http://blogs.discovermagaz
ine.com/80beats/2010/08/26/when-caterpillars-attack-tobacco-plants-use-thei
r-own-spit-against-them/
There must be a reason nature wants this plant
left alone. But there is, and pharma knows it!
Thanks for your insightful comment. Virginia tobacco is easy to grow and
fortunately legal in this jurisdiction, and is a very different substance
to the enslaved and commodified versions available for ale in shops.
Without true legalisation cannabis will be enslaved in the same manner;
decriminalisation simply isn't good enough and most such proposals are
merely methods of raising revenue via taxation and licensing. These weeds
must be allowed to flourish and grow unimpeded, like the people who use
them. The causes of cancers attributed to tobacco are in fact multifarious
- not least the incredibly multiplex brew of noxious poisons used in
growing and 'curing' the plant. In the US radioactive waste was even
sprayed on the plants by corporations who own nuclear power plants and
tobacco crops.
However, you're correct when you state that fear mongering is the true
killer brainwashing tool; we create our own reality, and that includes the
state of our health. The placebo effect works for good or ill - a fact few
seem to recognise.